African and European multidisciplinary researchers established an integrated consortium to develop a research project on the dengue and Zika viruses affecting Africa and the world

Dengue and Zika viruses are arboviruses primarily transmitted by Aedes mosquitoes. Dengue and Zika infectious disease frequently erupt in tropical and subtropical regions. Globalization coupled with climate change, significantly expedites their worldwide dissemination, often sparking new epidemics.

WHO reported the highest number of dengue cases (~6.5 million in 2023) in over 80 countries with 7300 dengue-related deaths. Burkina Faso and Mali have been reported to be among 8 countries with active cases in 2023, while Burkina Faso accounted for about 74% of total numbers of cases. Tanzania’s first confirmed Dengue outbreak occurred in 2010 in Dar es Salaam, since then, several outbreaks have occurred. Furthermore, first confirmed cases of Zika in Tanzania were reported in 2016 and in 2022. Incidence of dengue and Zika fever often spikes in rainy seasons mostly in urban settings.

Understanding how dengue and Zika viruses interact and affect individuals and populations is crucial for disease management and prevention, given their frequent co-circulation and potential for compounded clinical outcomes. The interplay between these viruses can complicate clinical picture, potentially leading to atypical or severe disease presentations.

Identifying and analyzing drivers of dengue and Zika virus spread in regions lacking sufficient epidemiological, immunological, and entomological data is critical for effective surveillance and control. Variations of these infections transmission in the three countries provides a unique opportunity to investigate genetic diversity of vectors and viruses, immunology and molecular interplay influences clinical outcome and co-circulation.

HORIZON-JU-GH-EDCTP3-2024-01-06-two-stage Call successful submission

A consortium composed by University of Sciences, Technologies and Techniques of Bamako (USTTB, Mali), Ministry of Health of Burkina Faso,  University of Bordeaux (France), and Fondazione Bruno Kessler (FBK, Italy) as Project Partners and managed by R-Evolution Worldwide as Project Coordinator has successfully submitted a proposal in the field of Digital Health for the HORIZON-JU-GH-EDCTP3-2024-01-06-two-stage Call.

The project name is “LINKAGE: InteroperabLe combination of existing dIgital solutions to improve the deliveriNg of Key healthcare services, nAtional control proGrams for vulnerablE populations of Mali and Burkina Faso”.

The project’s major ambition is the improvement of Antenatal Care services (ANC) in Mali and Burkina Faso through making interoperable with each other already existing open-source digital platforms: BOGOU, DHIS2 and TreC Mamma. It will greatly improve health outcomes by enhancing accessibility to ANC information at different levels and to different stakeholders such as health professionals, mothers, policy makers and researchers.

By integrating strengths and key functionalities from existing platforms and adopting a structured business intelligence approach, the project will support the scaling-up of new digital technologies in public health interventions, serving as drivers for the strengthening of health systems in SSA. By enabling the efficient exchange of information and promoting collaboration among stakeholders, the digital solution approach of the project can help streamline processes, improve healthcare delivery, and ultimately contribute to the overall improvement of healthcare systems in the region.

Indeed, the envisioned approach will be explored to benefit other potential countries and the scaling-up in other regions of SSA as well.

R-Evolution Worldwide as part of a multidisciplinary team of African and European researchers developed the VectorEnd project.

The increasing urbanization in Africa, paralleled by inadequate environmental sanitation, significantly contributes to the proliferation of Aedes mosquitoes, which transmit many arboviruses, including dengue virus (DENV) and Chikungunya virus (CHIKV).

In  2023, a total of 70 223 cases of dengue and 753 deaths have been reported from 15 African countries. Burkina Faso continues to be the country most impacted, accounting for 85% of reported cases and 91% of recorded fatalities. In 2023 Mali experienced simultaneous outbreaks of dengue and chikungunya infections.

The VectorEnd project promotes  an integrated vector control approach to mitigate the burden of dengue and chikungunya, in urban areas of Burkina Faso, Mali, and Tanzania with high incidences of these diseases.

This initiative marks the first comprehensive trial in African urban settings to assess the combined effect of mass trapping, larval source management, and community engagement on controlling Aedes mosquitoes and the diseases they transmit.

INTEGRATION Annual Project Meeting Y3

The INTEGRATION consortium held its annual meeting of the third year of the project on 21st and 22nd March 2024 in Paris. The INTEGRATION project involves the University of Sciences, Techniques and Technologies of Bamako, USTTB (Mali), CNRST-Centre National De La Recherche Scientifique et Technologique/IRSS-Institut de Recherche en Sciences de la Santé (Burkina Faso), Institut de Recherche pour le Développement, IRD (France), Liverpool School of Tropical Medicine, LSTM (United Kindom) and R-Evolution Worldwide Srl – Impresa Sociale, R-evoWW (Italy).

Click here for more information:  Annual Project Meeting Y3 – INTEGRATION (

NeuroSolve Project Kick-off Meeting in Lusaka, Zambia

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The NeuroSolve consortium held its Project Kick-off Meeting on the 4th December 2023 in Lusaka (Zambia). NeuroSolve is a four-year project funded by EDCTP3, lead by an African-European research consortium involves the University of Dar es Salaam (UDSM – Tanzania), Sokoine University of Agriculture (SUA – Tanzania), University of Zambia (UNZA – Zambia), Revolution Worldwide Srl – Impresa Sociale (R-EvoWW – Italy) and Universiteit Ghent (UGent – Belgium).

Third International Conference on Public Health in Africa

The third edition of CPHIA was hosted by the Zambian Ministry of Health and took place from 27th to 30th November 2023 at Mulungushi International Conference Center in Lusaka, Zambia.

The topic of the conference “Breaking Barriers: Repositioning Africa in the Global Health Architecture” was explored across nine plenary sessions, several parallel and abstract sessions and dozens of official side events. CPHIA 2023 was one of the largest global public health events because involved 40 different nations with over 5000 delegates who attended the conference in person and over 20,000 virtually. Part of the R-evoWW team took part in the event.

Eleventh EDCTP Forum

R-evoWW took part to the Eleventh EDCTP Forum in the Palais des Congrès de Paris in Paris (France) from 7th to 10th November 2023.

This Forum marked EDCTP’s 20th Anniversary and the theme was “Partnering for Global Health Research Innovation and Impact in Africa – Celebrating EDCTP: two decades and beyond”.

INTEGRATION Annual Project Meeting Y2-Rome

The INTEGRATION consortium held its annual meeting of the year 2 of the project on 6th and 7th March 2023 in Rome, Italy. During the meeting, the progress of the project was presented by the different members of the consortium.

Professor Andrea Crisanti (Full Professor of molecular parasitology at Imperial College in London – Department of Life Sciences and Senate of the Italian Republic) also took part in the event with a plenary speech on scientific advances in the manipulation of the natural selection of mosquitoes to disrupt the reproductive capacity of malaria vectors.

Second International Conference on Public Health in Africa


The Second International Conference on Public Health in Africa (CPHIA) was held in Kigali on 13th-15th December 2022.

In CPHIA 2022 conference were addressed discussion on need to ensure global health security. The conference also offered dedicated tracks focused on progress in the areas of digital health technologies, local vaccine manufacturing capacity, as well as all concerning HIV, TB, Malaria and Non-Communicable Diseases, and the need of strengthening of health system for equitable and universal health African coverage. In the conference related issues were addressed equity and inclusion, dedicated totally to Woman in Health, as, also the importance of public-private partnership in enhancement of overall health response.

During this conference R-evoWW had the opportunity to present the results of INTEGRATION project.

INTEGRATION – Project Kick-off Meeting

The INTEGRATION consortium held its kick-off meeting on 22nd and 23rd November 2021 both in person at Hôtel l’Amitié, Bamako, Mali, and virtually. The main purpose of the meeting was to offer the opportunity to exchange knowledge and practices between the INTEGRATION researchers, stakeholders and policymakers, as well as to have a common understanding of the study and any key questions during the study implementation in the routine health systems in Burkina Faso and Mali.

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