In a Controlled Human Infection Model (CHIM) study, a well-characterised strain of an infectious agent is given to carefully selected adult volunteers in order to better understand human diseases, how they spread, and find new ways to prevent and treat them. These studies play a vital role in helping to develop vaccines and treatments for infectious diseases.

A very important application of the se studies are the field of malaria clinical research. Indeed in the Controlled human malaria infection (CHMI) studies, healthy volunteers are infected with Plasmodium falciparum to assess the efficacy of novel malaria vaccines and drugs, becoming a vital tool to accelerate vaccine and drug development.

Leave a Reply

Your email address will not be published. Required fields are marked *

Explore More

SEARCH project kick-off meeting

After months of intense preparation, the SEARCH (SouthErn Africa Regulatory for Clinical researcH) will have its project kick-off meeting. The Partners from all countries of SEARCH Consortium (Mozambique, Botswana, Eswatini,

SUPER

The SUPER project will provide capacity building at the regulatory and ethics level for National Regulatory Authority, National and Institutional Ethics Committees, with the ultimate goal to strengthen an environement

SEARCH

SEARCH (SouthErn Africa Regulatory for Clinical researcH) is a consortium of Southern African countries (Mozambique, Swaziland, Lesotho and Botswana) and European Union, aimed to increase the capacity of the National