In a Controlled Human Infection Model (CHIM) study, a well-characterised strain of an infectious agent is given to carefully selected adult volunteers in order to better understand human diseases, how they spread, and find new ways to prevent and treat them. These studies play a vital role in helping to develop vaccines and treatments for infectious diseases.

A very important application of the se studies are the field of malaria clinical research. Indeed in the Controlled human malaria infection (CHMI) studies, healthy volunteers are infected with Plasmodium falciparum to assess the efficacy of novel malaria vaccines and drugs, becoming a vital tool to accelerate vaccine and drug development.

Leave a Reply

Your email address will not be published. Required fields are marked *

Explore More

INTEGRATION, an intervention research to protect pregnant women from malaria

Pregnant women, babies and children under 5 years of age are the most vulnerable to malaria. In 2018, around 11 million pregnant women and 24 million children got malaria. Furthermore,

A multidisciplinary consortium of African and European researchers responded to the urgent call from the European Union by developing a research project on the current Monkeypox outbreak in central Africa.

The spread of Mpox virus (MPXV) in Sub-Saharan Africa, specifically Democratic Republic of Congo (DRC) and Republic of Congo (RoC) presents an urgent public health concern with global implications. MPXV cases

From 2003 at the forefront of supporting Sub-Saharan Africa’s response to poverty-related infectious diseases, EDCTP plays a key role also in the African response to Covid-19

The European & Developing Countries Clinical Trials Partnership (EDCTP) is a public-public partnership between countries in Europe and sub-Saharan Africa, supported by the European Union, which since 2003 has been