Indirect effects of the COVID-19 pandemic on malaria in Africa

In Africa, pregnant women and young children are the most vulnerable to malaria.

However, malaria control interventions and strategies have achivied important results in the last years.

COVID-19 has now made these interventions critical, and could undo the results obtained so far, as highlighted by scientists in the Lancet: https://bit.ly/2Tfyxwn.

Potentially, COVID-19 could indirectly cause more deaths than it already does directly, in the context of Africa’s weak and fragile health systems.

INTEGRATION, an intervention research to protect pregnant women from malaria

Pregnant women, babies and children under 5 years of age are the most vulnerable to malaria. In 2018, around 11 million pregnant women and 24 million children got malaria. Furthermore, the WHO estimates that due to Covid-19 there will be disruptions in the fragile national health systems that could lead to a doubling of malaria mortality this year, from 400,000 to about 800,000 deaths, more than those from Covid-19 itself.

INTEGRATION project is an intervention that strategically integrates malaria prevention treatments for pregnant women and children to change African national health prevention policies and protect millions of pregnant women from malaria every year.

INTEGRATION project has been developed by a consortium of universities, research institutes and NGO from 2 African countries (Burkina Faso and Mali) and 3 European countries (France, England and Italy), which submitted this research project to the European Commission (EDCTP).

Donne in gravidanza, neonati e bambini sotto i 5 anni di età sono i più vulnerabili alla malaria. Nel 2018, circa 11 milioni di donne in gravidanza e 24 milioni di bambini si sono ammalati di malaria. Inoltre, l’OMS stima che a causa del Covid-19 ci saranno disfunzioni nei fragili sistemi sanitari africani che potrebbero portare quest’anno a un duplicarsi della mortalità per malaria, passando da 400.000 a circa 800.000 morti, ben di più di quelli causati dal Covid-19 stesso.

INTEGRATION è un intervento che integra strategicamente i trattamenti di prevenzione della malaria per donne in gravidanza e bambini, in modo da potenzialmente cambiare le politiche di prevenzione sanitaria in Africa e proteggere dalla malaria per milioni di donne in gravidanza ogni anno.

INTEGRATION è nato da un consorzio di università, istituti di ricerca e ONG di 2 paesi africani (Burkina Faso e Mali) e 3 paesi europei (Francia, Inghilterra e Italia), che hanno presentato questo progetto al bando di ricerca alla Commissione Europea (EDCTP).

Response to Covid-19 in Africa

The impact of Covid-19 in Africa is a ticking bomb on which the European Union (EDCTP) intervenes by supporting research projects. In response to this, a consortium of African and European universities and research institutes developed the ITAIL-COVID-19 project, aimed at implementation of novel and integrated laboratory testing approaches as a strategy against the spread of SARS-COV-2 in the Republic of Congo.

AfriNEXT

AfriNEXT project aims to develop and promote a vibrant, strong and sustainable research culture Africa. The project will create a critical mass of African world-class researchers capable of carrying out high quality research on local health priorities with a strong emphasis on maternal and child health. It is a great pleasure to collaborate with research and academic hubs of Burkina Faso, Ghana, Guinea, Cameroon, the Democratic Republic of Congo and Ethiopia, lead by Prof. Seni Kouanda.

Neglected Tropical Diseases research project in Benin and Togo

R-Evolution Worldwide had the exciting opportunity to collaborate with a great team of rappresentatives from the Ministries of Health of Benin and Togo in the research project proposal: “Impact of self-care groups on stigma among Leprosy and Buruli ulcer patients in Benin and Togo”. Thank you to all the team, lead by Dr. Yves Thierry Barogui.

SUPER

The SUPER project will provide capacity building at the regulatory and ethics level for National Regulatory Authority, National and Institutional Ethics Committees, with the ultimate goal to strengthen an environement favourable for the clinical research addressing the burden of diseases in the Eastern African region. The project is coordinated by EACCR, the Network of Excellence in clinical research for Eastern African region, lead by Dr. Pontiano Kaleebu.

ImproViTB

With 1 million new cases and 200,000 children dead each year, Tuberculosis (TB) is now the leading cause of death from infectious diseases for children of all ages globally (UNICEF). ImproViTB is among the first pediatric clinical studies in the Central African region aimed at improving the clinical outcome and quality of life of children with pulmonary tuberculosis through a standard antituberculosis treatment supplemented with vitamin D.
This project is lead by a consortium of research institutions and universities from 4 Central African countries (Republic of Congo, Democratic Republic of Congo, Cameroon and Gabon) and 3 European countries, coordinated by CANTAM (Prof. Francine Ntoumi), the Network of Excellence in clinical research for Central African region.

SEARCH

SEARCH (SouthErn Africa Regulatory for Clinical researcH) is a consortium of Southern African countries (Mozambique, Swaziland, Lesotho and Botswana) and European Union, aimed to increase the capacity of the National Regulatory Authorities to oversight clinical trials for new, safer and more effective medicines to treat the diseases affecting the Southern African region. The consortium is coordinated by TESA, the Network of Excellence in clinical research for Southern African region, lead by Dr. Eusebio Macete.

INTEGRATION+

INTEGRATION+ is an implementation research focused on malaria in pregnancy, with the potential to change national health prevention policies to protect an additional 13 million pregnant women each year from malaria. A consortium of universities and research institutions from 6 African countries and 2 European countries applied to fund this project to European Commission (EDCTP) and USA (PMI).

AfriEthique

A European-African partnership aimed at improving the ethics and regulatory capacity of clinical research in Central African countries has successfully proposed its project (AfriHetique) to the European Commission (EDCTP). The partnership is coordinated by CANTAM, the Network of Excellence in clinical research for Central African region, lead by Prof. Francine Ntoumi.