SEARCH (SouthErn Africa Regulatory for Clinical researcH) is a consortium of Southern African countries (Mozambique, Swaziland, Lesotho and Botswana) and European Union, aimed to increase the capacity of the National Regulatory Authorities to oversight clinical trials for new, safer and more effective medicines to treat the diseases affecting the Southern African region. The consortium is coordinated by TESA, the Network of Excellence in clinical research for Southern African region, lead by Dr. Eusebio Macete.