IntegraCLIM is a research and implementation initiative aimed at evaluating the cost-effectiveness and operational feasibility of an integrated climate-adaptive intervention package designed to reduce climate-sensitive infectious diseases in sub-Saharan Africa. 

The project will be implemented in climate-vulnerable districts of Ethiopia and Burkina Faso, where recurrent floods, droughts, and heatwaves are contributing to the increasing transmission of arboviral diseases such as dengue, chikungunya, and yellow fever, as well as water-borne diseases including cholera, typhoid, and rotavirus, particularly among vulnerable populations.

The project will assess an integrated intervention strategy combining enhanced vector control measures, strengthened household and community WASH interventions, and climate-informed decision-support tools integrated into district early warning systems. Through a cluster randomised controlled trial, the project will compare routine national practices with an intervention delivered through primary healthcare services and community-based platforms, with the objective of improving outbreak prevention, accelerating response times, and strengthening health outcomes. 

IntegraCLIM also incorporates advanced modelling of climate–disease dynamics using meteorological, environmental, entomological, and surveillance data within a One Health framework, generating operational indicators and trigger thresholds to support climate-adaptive public health decision-making.

The proposal is coordinated by R-Evolution Worldwide and involves an international consortium including Bahir Dar University (Ethiopia), Jimma University (Ethiopia), Centre National de Recherche Scientifique et Technique (Burkina Faso), London School of Hygiene and Tropical Medicine (United Kingdom), the International Institute for Applied Systems Analysis, and the Vibranium Resources Foundation, bringing together expertise in climate science, infectious diseases, implementation research, and global health systems.